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KMID : 0387419980090020045
Korean Society of Oriental Neuropsychiatry
1998 Volume.9 No. 2 p.45 ~ p.51
The Experimental Study on the Effects of Hangbujapalmultang on Enhangcing Learning and Memory in Rats with Radial Arm Maze





Abstract
Purpose : This study has an experiment on finding how Hyangbujapamultang advanced the learning and memory of rat to find the method to improve the failure of memory which is the symptom of dementia.
Method : In the experiment, rats were divided the control group (14 rat) which medicate the excipient into the sample group (17 rat) which medicates Hyangbujapalmutang. And the learning ability test and the memorv test was practiced to using the task of radial arm maze.
The learning ability test had the presupposition that, when a rat which frequents 8 tracks makes am error not exceeding one time for 3 days without a break, it passes the test.
First experiment compared total days when the control group passed the test with total days when the sample group it.
The memory test practiced after 24 hours when the learning ability test was over. When a rat frequents 4 tracks, the gates is cut off during 30 seconds. Here the number of error at the control group with that of the sample group.
Result: In the learning ability test, the sample group needed 5.82¡¾0.37 days to pass the test and the control group needed 6.43¡¾0.67 days. In the memory test, the sample group errored 0.29¡¾0.37 times and the control group errored 1.86¡¾0.78 times.
Conclusion : In the learning ability test, the sample group passed the test earlier than the control group, but any statistical correlationship couldn¢¥t be found in it. In the memory test, the sample group had the pregnant reduction of the number of error in comparison with the control group.
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